产品货号：
Z33612
中文名称：
CA15-3/MUC1抗体
英文名称：
Anti-CA15-3/MUC1 Antibody (Clone#GP1.4)
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-CA15-3/MUC1 Antibody (Clone#GP1.4) |
| 指标别名 | CA15 3;CA153;CA15-3;Carcinoma associated mucin;CD227;EMA;Episialin;H23AG;KL-6;MAM6;MUC 1;MUC1;MUC1 beta;MUC1 CT;MUC1 NT;MUC1/CA15-3 C-terminal;Mucin 1;Peanut reactive urinary mucin;PEM;PEMT;Polymorphic epithelial mucin;PUM;Tumor associated mucin |
| 克隆性 | Monoclonal |
| 检验物种 | human |
| 应用范围 | IHC,IHC-F |
| 基因名称 | MUC1 |
| 克隆号 | GP1.4 |
| 抗体来源 | Mouse |
| 抗体类型 | IgG1 |
| 免疫原 | Human milk fat globule membranes. |
| 成分 | 200μg/mL antibody with PBS，0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | Ascites |
| 浓度 | 200μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | MUC1 is a large cell surface mucin glycoprotein expressed by most glandular and ductal epithelial cells and some hematopoietic cell lineages.It is expressed on most secretory epithelium,including mammary gland and some hematopoietic cells.It is expressed abundantly in lactating mammary glands and overexpressed abundantly in>90% breast carcinomas and metastases.Transgenic MUC1 has been shown to associate with all four cebB receptors and localize with erbB1(EGFR) in lactating glands.The MUC1 gene contains seven exons and produces several different alternatively spliced variants.The major expressed form of MUC1 uses all seven exons and is a type I transmembrane protein with a large extracellular tandem repeat domain.The tandem repeat domain is highly O glycosylated and alterations in glycosylation have been shown in epithelial cancer cells. |
| Uniprot ID | P15941 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Mouse IgG (ZN1928) for Western blot,and HRP Conjugated anti-Mouse IgG Super Vision Assay Kit (ZN1866) for IHC(P) and ICC. |
| 基因名全称 | mucin 1,cell surface associated |
| 蛋白名全称 | Mucin-1 |
| 推荐稀释比 | Immunohistochemistry in paraffin section (IHC) 1:50～400 Immunohistochemistry in frozen section (IHC-F) 1:50～400 (Boiling the paraffin sections in 10mM citrate buffer,pH6.0,or PH8.0 EDTA repair liquid for 20 mins is required for the staining of formalin/paraffin sections.) Optimal working dilutions must be determined by end user. |
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